“It has become increasingly clear that children are less frequently affected by severe COVID-19 than adults. However, a new ‘hyperinflammatory syndrome’ in children associated with SARS-CoV-2 has recently been widely reported in the media with notable clusters of cases in New York City and London. This review will outline what we know so far about this new syndrome and what it means for us as clinicians.

This hyperinflammatory syndrome has similarities to Kawasaki disease, Toxic Shock Syndrome, and hyperinflammatory syndromes such as Haemophagocytic Lymphocytic Histiocytosis (HLH) and SLE. “

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